REGINA LOCUS LVXL
JA
Sérum Renaissance Beauté

STEP 2 · Protect ／ Serum

Sérum Renaissance Beauté

BSB Innovation Awards 2025 Winner. Rebuilding the barrier.

World's highest concentration of Ceradrop — BSB Innovation Awards 2025 winner. A high-performance aging care serum aimed at fundamental barrier function repair.

¥22,00030 mL ／ About 1 month
1
Free shipping within Japan on orders of ¥10,000 or more
Keeping moisture inside the wall

WHAT MAKES IT DIFFERENT

What makes this product different.

  • No.1Ceradrip, first place at the BSB Innovation Awards 2025
  • 3Rich in phospholipids, glucosylceramide and ceramides
  • 28dLasting barrier improvement confirmed after 28 days of use
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Ceradrop is a cutting-edge barrier repair ingredient that won first place at BSB Innovation Awards 2025. Rich in phospholipids, glucosylceramides, and ceramides derived from Torula yeast, it fundamentally repairs the skin's barrier function.

This product contains Ceradrop at the world's highest concentration. A single application produces immediate improvement in skin softness and firmness, with sustained barrier improvement confirmed over 28 days of use.

The purpose is long-term reconstruction of barrier structure rather than immediate effect.

FORMULATION

Third in the cascade: working on the gaps in the wall.

Designed for the B (barrier) axis.

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Designed as a product addressing the B-axis (Barrier axis). In CHROSNOF analysis, the barrier axis is the "foundational condition" for other aging mechanisms to progress.

No matter how premium the ingredients applied to skin with a non-functional barrier, the effects are limited. Restore the barrier first. That is the role of this product.

RIBFASRustSmouldering fireGaps in the wallUnravelling netScorchOld cellsWorks here

FULL DISCLOSURE

All 25 ingredients, disclosed.

Listed in order of formulation, in full. Coloured entries carry one of the FABIRS axes.

  • R Antioxidation
  • B Barrier
  • F Fibroblast
  • Base & formulation matrix
  1. 01Water
  2. 02 · BSqualane
  3. 03Rosa Damascena Flower Water
  4. 04Pentylene Glycol
  5. 05Butylene Glycol
  6. 06 · BCyberlindnera Phospholipids
  7. 07 · BDihydroxypropyl Arginine HCl
  8. 08 · Fsh-Oligopeptide-1
  9. 09 · BCeramide NG
  10. 10 · BCeramide NP
  11. 11 · BCeramide AP
  12. 12Acetyl Hexapeptide-8
  13. 13 · FPalmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine
  14. 14 · FPalmitoyl Dipeptide-5 Diaminohydroxybutyrate
  15. 15 · FPalmitoyl Tripeptide-5
  16. 16Dipeptide Diaminobutyroyl Benzylamide Diacetate
  17. 17Glycerin
  18. 18 · BPhytosterols
  19. 19Hydrogenated Lecithin
  20. 20 · BCholesterol
  21. 21Xanthan Gum
  22. 22 · RTocopherol
  23. 23Caprylyl Glycol
  24. 24Phenoxyethanol
  25. 25Fragrance

Publishing the full list in order is the surest proof that the money went into the raw materials.

FOR YOU

This product is for you if.

  • You have chronic skin dryness or instability
  • Your skin has become sensitive or reactive
  • You struggle to feel effects from any product
  • Your skin feels thinner with age
  • You want to rebuild the foundation of your skincare

HOW TO USE

How to use.

  1. 01Use after cleansing, once toner has prepared the skin.
  2. 02Take a suitable amount in your palm.
  3. 03Blend across the entire face, then layer on areas of concern.
  4. 04Can be used morning and night.

SEQUENCE ／ Order of use

Ageing has an order. So does care.

  1. 00 · CLEANSEMousse Purifiante LumièreCleansing ／ Available
  2. 01 · STEP 1Essence Sérénité ProfondeEssence ／ Coming Soon
  3. 02
    STEP 1Concentré Revitalisant AvancéConcentrate ／ Available
    STEP 2 — This productSérum Renaissance BeautéSerum ／ Available
  4. 03 · STEP 3Crème Régénération TemporelleCream ／ In Development
  5. + INNERTisane Lumière IntérieureTisane ／ In Development
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First bring R (antioxidation) and I (inflammation) down to set the condition. Then rebuild B (barrier) to establish the foundation. Finally raise F (fibroblast) while holding A (anti-glycation) and S (senescence control) down to close the sequence. The order of the routine is the order of the chain. With oxidation and inflammation still in place, nothing layered on top will work. Set the condition first. Building comes after.

FAQ

Frequently asked questions about this product.

Can sensitive skin use this?

This product was developed with sensitive skin in mind as its primary user, due to its barrier repair purpose. However, a patch test is recommended for first use.

What order should I layer with other products?

Cleanser → toner → serums (this product and Concentré Revitalisant Avancé) → cream. Use serums after toner; the two serums can go in either order.

How soon will I notice a change?

Barrier repair relies on continuity more than immediacy. The guideline is 4–8 weeks of consistent use.

Purchase¥22,000
1
Free shipping within Japan on orders of ¥10,000 or more

ANOTHER FORMULATION

FABIRS — what the six letters stand for

  • F — Fibroblast ／ 線維芽細胞活性化
  • A — Anti-Glycation ／ 抗糖化
  • B — Barrier ／ バリア強化
  • I — Inflammation ／ 抗炎症
  • R — Antioxidation ／ 抗酸化
  • S — Senescence Control ／ 老化細胞の蓄積抑制

The effect of topical application on senescent cells in human skin is an area where verification is still in progress. CHROSNOF treats S as an axis within its calculations and makes no numerical claim regarding the amount of senescent cells or any end state.