R-axis / Antioxidant · Fullerene
Concentré Revitalizon Avancé Base de Liposomes
World's highest concentration fullerene 10%. 250x the antioxidant power of Vitamin C.
¥12,800Learn More →
Why REGINA LOCUS LVXL
Zero advertising. Every yen into ingredients.
Since founding in 2012, this brand has spent nothing on advertising. Every resource goes entirely into ingredient sourcing. We choose formulations honest to the reality of aging, not formulations that sell easily.
2012
Founded
¥0
Advertising spend
100%
Into ingredients
Signature Products
Two honest formulations.
Each directly addresses a distinct mechanism of skin aging.
The Limits of Conventional Skincare
Why ordinary skincare does not reach deep enough.
01
ROS (Reactive Oxygen Species) Cascade
The oxidative stress-driven destruction of collagen cannot be halted by moisturizers alone. Materials with antioxidant mechanisms are required.
02
AGEs (Advanced Glycation Endproducts) Accumulation
Aging caused by protein glycation cannot be reversed by surface-level care. A structural approach is necessary.
03
Compromised Formulation Concentration
Most products list ingredients but use negligible concentrations. We use only concentrations where efficacy has been confirmed.
The Evidence for Skin Longevity
Aging follows a sequence. Which means it can be addressed in the right order.
ROS → inflammation → MMP → collagen destruction → AGE accumulation. Understanding these five pathways is where real skin longevity begins.
Understand the Five Pathways →Responding to aging with materials that understand it.
From two formulations, find the one that meets your skin's challenge.